Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201458 | 0.77 | LMNA (0.33) | P2RX4P2RX1P2RX3MAPK1LMNA | |
| SCHEMBL22879494 | 0.73 | KMT2A (0.37) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| SCHEMBL26811011 | 0.73 | P2RX4 (0.39) | P2RX4MTNR1AMTNR1BP2RX1P2RX3 | |
| SCHEMBL24201420 | 0.72 | P2RX4 (0.40) | P2RX4MTNR1AMTNR1BP2RX1P2RX3 | |
| SCHEMBL19198881 | 0.72 | HSD17B3 (0.42) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| SCHEMBL1198914 | 0.65 | P2RX4 (0.37) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| SCHEMBL29434173 | 0.65 | P2RX4 (0.37) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| SCHEMBL12013901 | 0.65 | HTR1A (0.36) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| Iodide SCHEMBL7101346 | 0.64 | P2RX4 (0.36) | HTR1ADRD2HTR2AHTR6SLC6A4 | |
| Hydrochloric Acid SCHEMBL29035745 | 0.64 | MEN1 (0.37) | HTR1ADRD2HTR2AHTR6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230176063-A1 | PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES | ACADEMIA SINICA (TW) | 2023-06-08 | — | — | US | disclosed |
| EP-3613755-A1 | LYSINE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS USING MICROBIAL TRANSGLUTAMINASE | Novartis AG (CH) | 2020-02-26 | — | — | EP | disclosed |