Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 6/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769423 | 0.86 | FGFR2 (0.57) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL21769162 | 0.85 | MET (0.56) | FGFR2PDGFRAPDGFRBKDRMET | |
| SCHEMBL19372928 | 0.84 | PDGFRA (0.54) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL22104168 | 0.84 | FGFR2 (0.58) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL7480589 | 0.84 | FGFR2 (0.73) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL23584982 | 0.83 | MET (0.65) | PDGFRAKDRMET | |
| SCHEMBL21769294 | 0.81 | PDGFRA (0.59) | FGFR2PDGFRAPDGFRBKDRMET | |
| SCHEMBL30106512 | 0.80 | PDGFRB (0.59) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL21753513 | 0.80 | PDGFRB (0.59) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL23617110 | 0.80 | FGFR2 (0.67) | FGFR2PDGFRAKDRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |