Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769528 | 0.95 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL21769246 | 0.92 | FNTA (0.43) | ALDH1A1MAPK1NPSR1FNTAFNTB | |
| SCHEMBL21769409 | 0.87 | KDM4E (0.40) | ALDH1A1MAPK1NPSR1FNTAFNTB | |
| SCHEMBL21769491 | 0.87 | FNTA (0.41) | ALDH1A1FNTAFNTBSMN1; SMN2KDM4E | |
| SCHEMBL21769485 | 0.87 | FNTA (0.41) | ALDH1A1FNTAFNTBSMN1; SMN2KDM4E | |
| SCHEMBL21769249 | 0.85 | MAPT (0.41) | ALDH1A1MAPK1NPSR1FNTAFNTB | |
| SCHEMBL21769498 | 0.85 | HSD17B10 (0.40) | ALDH1A1KMT2AMEN1NPSR1FNTA | |
| SCHEMBL21769530 | 0.85 | ESR1 (0.44) | ALDH1A1KMT2AMEN1MAPK1FNTA | |
| SCHEMBL21769463 | 0.83 | KDM4E (0.44) | ALDH1A1NPSR1SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL21440788 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1SMN1; SMN2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | ALDH1A1 1721/4885KMT2A 4291/4885MEN1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.