Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769234 | 0.92 | KDM4E (0.57) | KDM4EPOLBHTTBLMALDH1A1 | |
| SCHEMBL21769464 | 0.88 | DRD3 (0.48) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL21769465 | 0.87 | KDM4E (0.49) | KDM4EPOLBALDH1A1DRD3 | |
| SCHEMBL21769527 | 0.84 | ALDH1A1 (0.46) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL21769241 | 0.83 | KDM4E (0.52) | KDM4EPOLBHTTBLMALDH1A1 | |
| SCHEMBL21769525 | 0.83 | USP2 (0.50) | KDM4EPOLBALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL21769539 | 0.83 | KDM4E (0.52) | KDM4EPOLBHTTBLMALDH1A1 | |
| SCHEMBL21769246 | 0.83 | FNTA (0.43) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21769409 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21769463 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | KDM4E 3638/4885POLB 2907/4885HTT 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.