Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923453 | 0.94 | MAPT (0.35) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL17923449 | 0.91 | SMN1; SMN2 (0.36) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21769738 | 0.90 | HDAC1 (0.39) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21769573 | 0.89 | POLB (0.39) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21769854 | 0.89 | KMT2A (0.39) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL17923455 | 0.88 | MAPT (0.37) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21769571 | 0.88 | SLC6A9 (0.36) | MAPTSLC6A9SLC6A5 | |
| SCHEMBL21769874 | 0.88 | MAPT (0.38) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21769731 | 0.87 | KMT2A (0.40) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL21769885 | 0.86 | POLB (0.37) | MAPTNPSR1KDM4EALDH1A1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |