Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815306 | 0.84 | HTT (0.39) | HTTSCN4AGLASMN1; SMN2P2RX7 | |
| SCHEMBL28459274 | 0.80 | GAA (0.36) | HTTALDH1A1OPRM1KLF5MAPT | |
| SCHEMBL3724771 | 0.74 | CYP3A4 (0.35) | SCN4ASMN1; SMN2ALDH1A1OPRM1CYP2C9 | |
| SCHEMBL2815309 | 0.74 | HTT (0.39) | HTTSCN4AP2RX7OPRM1MAPT | |
| SCHEMBL14000159 | 0.71 | MAPT (0.37) | HTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29031636 | 0.71 | CNR2 (0.49) | HTTSCN4ASMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL11260320 | 0.70 | ALDH1A1 (0.52) | HTTGLASMN1; SMN2ALDH1A1NR1I2 | |
| SCHEMBL11871041 | 0.70 | CYP3A4 (0.37) | HTTSCN4AALDH1A1OPRM1MAPT | |
| SCHEMBL14000191 | 0.69 | SLC6A9 (0.43) | SLC6A9 | |
| SCHEMBL21769889 | 0.69 | HTT (0.39) | HTTSCN4ASMN1; SMN2ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |