Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815306 | 0.85 | HTT (0.39) | MAPTALDH1A1HTTOPRM1MEN1 | |
| SCHEMBL28460402 | 0.81 | MAPT (0.40) | GAAMAPTTDP1KDM4ETHRB | |
| SCHEMBL21769890 | 0.80 | HTT (0.36) | MAPTTHRBALDH1A1KLF5HTT | |
| SCHEMBL2815309 | 0.75 | HTT (0.39) | MAPTHTTOPRM1MEN1LMNA | |
| SCHEMBL9205663 | 0.72 | ALDH1A1 (0.57) | MAPTTDP1KDM4ENLRP3ALDH1A1 | |
| SCHEMBL14000159 | 0.71 | MAPT (0.37) | GAAMAPTALDH1A1L3MBTL1HTT | |
| SCHEMBL21769856 | 0.70 | L3MBTL1 (0.38) | MAPTTDP1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14000191 | 0.70 | SLC6A9 (0.43) | — | |
| SCHEMBL14000151 | 0.70 | TSHR (0.42) | MAPTTDP1KDM4ENLRP3ALDH1A1 | |
| SCHEMBL29031636 | 0.70 | CNR2 (0.49) | MAPTKDM4EALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623577-B | Preparation method of amonebvir and intermediate thereof | 山东百诺医药股份有限公司 | 2020-09-25 | — | — | CN | disclosed |