Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106419 | 0.87 | MAPT (0.65) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL5179212 | 0.83 | THRB (0.56) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL27641613 | 0.83 | SENP1 (0.57) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL2773071 | 0.81 | PPARA (0.59) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL131839 | 0.81 | CYP4F2 (0.56) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL3092388 | 0.80 | KMT2A (0.63) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL27976183 | 0.79 | CYP4F2 (0.55) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL5088971 | 0.78 | MAPT (0.55) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL29106420 | 0.78 | CDC25B (0.54) | SENP1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL5180814 | 0.78 | SENP1 (0.52) | SENP1KMT2AALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |