Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106419 | 0.88 | MAPT (0.65) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL5088971 | 0.84 | MAPT (0.55) | PPARAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL11238983 | 0.84 | MAPT (0.71) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2185832 | 0.84 | PPARA (0.58) | PPARAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2177009 | 0.81 | SENP1 (0.56) | PPARAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL2188996 | 0.81 | PPARA (0.79) | PPARAALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL3092388 | 0.81 | KMT2A (0.63) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL4106965 | 0.81 | TRPV1 (0.77) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL28007798 | 0.81 | RAB9A (0.73) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2186903 | 0.80 | PPARA (0.59) | PPARAMAPTALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |