Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 8/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634972 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28326979 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7645289 | 0.80 | TYMS (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8094143 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2712997 | 0.80 | TOP1 (0.62) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8080598 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28633753 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9768590 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL262473 | 0.78 | GSK3B (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28099802 | 0.78 | GSK3B (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519228-A2 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | Enzon Pharmaceuticals, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082368-A2 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | ENZON PHARMACEUTICALS, INC (US) | 2011-07-07 | — | — | WO | disclosed |
| EP-0766842-A1 | PHTHALIMIDE BLOCKED POST-PROCESSING STABILIZERS FOR PHOTOTHERMOGRAPHY | Imation Corp. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996000410-A1 | PHTHALIMIDE BLOCKED POST-PROCESSING STABILIZERS FOR PHOTOTHERMOGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-04 | — | — | WO | disclosed |