Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176940 | 0.80 | MAPT (0.43) | ALDH1A1L3MBTL1MAPTLMNANPC1 | |
| SCHEMBL2178503 | 0.78 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL2178071 | 0.77 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL6932995 | 0.74 | MMP1 (0.54) | ALDH1A1TDP1MAPTLMNANPC1 | |
| SCHEMBL2323676 | 0.74 | TP53 (0.43) | ALDH1A1L3MBTL1MAPTKCNA5TP53 | |
| SCHEMBL2363585 | 0.74 | TP53 (0.43) | ALDH1A1L3MBTL1MAPTKCNA5TP53 | |
| SCHEMBL2318294 | 0.74 | TP53 (0.43) | ALDH1A1L3MBTL1MAPTKCNA5TP53 | |
| SCHEMBL21926455 | 0.74 | MAPT (0.48) | ALDH1A1L3MBTL1TDP1MAPTLMNA | |
| SCHEMBL2177735 | 0.73 | KCNA5 (0.43) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL2179422 | 0.73 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |