SCHEMBL2177182

SCHEMBL2177182

O=C(O)CC(CO)C(=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MME P08473 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC1A1 P43005 1/20 0.34
CPA1 P15085 2/20 0.34
CPB1 P15086 1/20 0.34
CPA3 P15088 1/20 0.34
CPB2 Q96IY4 1/20 0.34
GABRR1 P24046 2/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22242591 0.86 FOLH1 (0.46) FOLH1SLC22A6TDP1MMESMN1; SMN2
SCHEMBL19615624 0.83 SLC1A1 (0.40) SLC1A1OR51E2
SCHEMBL542313 0.78 FOLH1 (0.56) FOLH1SLC22A6TDP1MMESMN1; SMN2
SCHEMBL9668057 0.77 MMP2 (0.40) FOLH1SLC22A6TDP1SMN1; SMN2SLC1A1
SCHEMBL28920282 0.76 FOLH1 (0.54) FOLH1SLC22A6TDP1MMESMN1; SMN2
Ammonia Solution, Strong SCHEMBL6779003 0.76 FOLH1 (0.54) FOLH1SLC22A6TDP1MMESMN1; SMN2
SCHEMBL9270192 0.74 MME (0.44) FOLH1SLC22A6TDP1MMESMN1; SMN2
SCHEMBL16115234 0.73 MME (0.49) FOLH1SLC22A6MMECPA1
SCHEMBL28324581 0.72 LMNA (0.41) FOLH1SLC22A6TDP1MMESMN1; SMN2
SCHEMBL16115238 0.72 MME (0.47) FOLH1SLC22A6MMECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120322906-A1 POLYMER AND METHODS OF PREPARING AND USING A POLYMER CARGILL, INCORPORATED (US) 2012-12-20 US disclosed
WO-2012166842-A1 INCREASING PRODUCT YIELD AND/OR THROUGHPUT BY SUPERSATURATION OF SUBSTRATE CARGILL, INCORPORATED (US) 2012-12-06 WO disclosed
WO-2012166406-A1 INCREASING PRODUCT YIELD AND/OR THROUGHPUT BY SUPERSATURATION OF SUBSTRATE CARGILL, INCORPORATED (US) 2012-12-06 WO disclosed
EP-2519406-A1 A POLYMER AND METHODS OF PREPARING AND USING A POLYMER Cargill, Incorporated (US) 2012-11-07 EP disclosed
US-20120270281-A1 BIOREACTOR PERFORMANCE IN THE PRODUCTION OF MONATIN CARGILL, INCORPORATED (US) 2012-10-25 US disclosed
US-20120264948-A1 MEMBRANE SEPARATION AND PURIFICATION OF MONATIN CARGILL, INCORPORATED (US) 2012-10-18 US disclosed
WO-2011082363-A1 MEMBRANE SEPARATION AND PURIFICATION OF MONATIN CARGILL, INCORPORATED (US) 2011-07-07 WO disclosed
WO-2011082353-A1 SEPARATION AND PURIFICATION OF MONATIN CARGILL, INCORPORATED (US) 2011-07-07 WO disclosed
WO-2011082365-A2 IMPROVED BIOREACTOR PERFORMANCE IN THE PRODUCTION OF MONATIN CARGILL, INCORPORATED (US) 2011-07-07 WO disclosed
WO-2011082351-A1 A POLYMER AND METHODS OF PREPARING AND USING A POLYMER CARGILL, INCORPORATED (US) 2011-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264948-A1 MEMBRANE SEPARATION AND PURIFICATION OF MONATIN MON2, STOM, MLEC FOLH1 1528/4885SLC22A6 2621/4885TDP1 4649/4885
US-20120322906-A1 POLYMER AND METHODS OF PREPARING AND USING A POLYMER MON2, STOM, LCP1 FOLH1 849/4885SLC22A6 3049/4885TDP1 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.