Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177182 | 0.86 | FOLH1 (0.41) | FOLH1SLC22A6TDP1SMN1; SMN2CPA1 | |
| SCHEMBL9668057 | 0.84 | MMP2 (0.40) | FOLH1SLC22A6TDP1SMN1; SMN2TSHR | |
| SCHEMBL16115234 | 0.80 | MME (0.49) | FOLH1SLC22A6CPA1MME | |
| SCHEMBL16115238 | 0.78 | MME (0.47) | FOLH1SLC22A6CPA1MME | |
| SCHEMBL8522829 | 0.77 | FOLH1 (0.43) | FOLH1SLC22A6TDP1SMN1; SMN2CPA1 | |
| SCHEMBL31040679 | 0.73 | GPR84 (0.58) | MAPT | |
| Tricarballylic Acid SCHEMBL1821947 | 0.73 | FOLH1 (0.65) | FOLH1SLC22A6TDP1SMN1; SMN2CPA1 | |
| Tricarballylic Acid SCHEMBL34866 | 0.73 | FOLH1 (0.65) | FOLH1SLC22A6TDP1SMN1; SMN2CPA1 | |
| SCHEMBL8417005 | 0.73 | SMN1; SMN2 (0.60) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL8416906 | 0.73 | SMN1; SMN2 (0.60) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231527-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | FURMAN UNIVERSITY | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231527-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | HOGA1, BCKDK, PCCA | FOLH1 3097/4885SLC22A6 1831/4885TDP1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.