SCHEMBL2177185

SCHEMBL2177185

O=C(O)CCCC(=O)OCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
SLC22A6 Q4U2R8 1/20 0.55
CAMK2A Q9UQM7 1/20 0.48
LMNA P02545 4/20 0.48
NFKB1 P19838 2/20 0.46
PMP22 Q01453 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
PAM P19021 2/20 0.42
GABRR3 A8MPY1 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
HDAC3 O15379 1/20 0.40
GABBR2 O75899 1/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10757164 0.95 LMNA (0.55) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL4079049 0.89 TSHR (0.48) TSHRLMNAPAMCYP1A2KMT2A
SCHEMBL638360 0.87 TSHR (0.43) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL1237232 0.84 LMNA (0.50) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL9558119 0.84 SLC22A6 (0.61) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL13224338 0.84 DGKA (0.48) TSHRLMNAPAMCYP1A2KMT2A
SCHEMBL2869946 0.82 TSHR (0.58) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL29231823 0.81 DGKA (0.52) TSHRLMNAPAMCYP1A2KMT2A
SCHEMBL4953488 0.81 TSHR (0.52) TSHRSLC22A6CAMK2ALMNANFKB1
SCHEMBL4669422 0.80 TSHR (0.56) TSHRSLC22A6CAMK2ALMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114280189-B Method for quickly and quantitatively analyzing fermentation metabolites of microbial cell factory 大连理工大学 2022-09-09 CN claimed
CN-114561312-B Recombinant yeast for synthesizing ursolic acid and construction method thereof 北京理工大学 2022-08-09 CN claimed
CN-114561312-A Recombinant yeast for synthesizing ursolic acid and construction method thereof 北京理工大学 2022-05-31 CN claimed
CN-112795495-B Method for producing heterologous cannabichromene by using saccharomyces cerevisiae 大连理工大学 2021-10-26 CN claimed
CN-112795495-A Method for producing heterologous cannabichromene by using saccharomyces cerevisiae 大连理工大学 2021-05-14 CN claimed
CN-122038157-A Engineering bacteria and method for synthesizing lacrimal alcohol 天津凯莱英生物科技有限公司 2026-05-15 CN disclosed
CN-119020170-B Monascus purpureus and application of selenium-enriched monascus prepared by same 西北大学 2025-06-10 CN disclosed
CN-119269659-A Application of urine organic acid in health management 欧湧淳 2025-01-07 CN disclosed
CN-119020170-A Monascus purpureus and application of selenium-enriched monascus prepared by same 西北大学 2024-11-26 CN disclosed
CN-118726121-A Recombinant pichia pastoris strain, construction method and application thereof 中国科学院大连化学物理研究所 2024-10-01 CN disclosed
CN-113930348-B Yarrowia lipolytica engineering strain for biosynthesis of glycyrrhetinic acid by taking glucose as substrate, construction and application thereof 河北维达康生物科技有限公司 2024-07-12 CN disclosed
CN-114958625-B Culture and preservation method of aspergillus terreus for producing lovastatin by fermentation 福安药业集团烟台只楚药业有限公司 2023-12-19 CN disclosed
WO-2009115652-A2 COMPOSITION AND METHODS USED DURING ANTI-HIV TREATMENT UNIVERSITE DE LA MEDITERANNEE, AIX-MARSEILLE II (FR) 2009-09-24 WO disclosed
WO-2009112653-A2 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION UNIVERSITE DE LA MEDITERRANEE, AIX-MARSEILLE II (FR) 2009-09-17 WO disclosed
US-20090099151-A1 Modified Release Pharmaceutical Compositions and Processes Thereof PANACEA BIOTEC LTD. (IN) 2009-04-16 US disclosed
EP-2034985-A1 COMBINATION OF AN HMG-COA REDUCTASE INHIBITOR AND A FARNESYL-PYROPHOSPHATASE SYNTHASE INHIBITOR FOR THE TREATMENT OF DISEASES RELATED TO THE PERSISTENCE AND/OR ACCUMULATION OF PRENYLATED PROTEINS Université de la Méditerranée - Aix-Marseille II (FR) 2009-03-18 EP disclosed
EP-1906932-A2 MODIFIED RELEASE PHARMACEUTICAL COMPOSITIONS ON THE BASIS OF TWO POLYMERS AND PROCESSES THEREOF Panacea Biotec Ltd. (IN) 2008-04-09 EP disclosed
WO-2008003864-A1 COMBINATION OF AN HMG-COA REDUCTASE INHIBITOR AND A FARNESYL-PYROPHOSPHATASE SYNTHASE INHIBITOR FOR THE TREATMENT OF DISEASES RELATED TO THE PERSISTENCE AND/OR ACCUMULATION OF PRENYLATED PROTEINS UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) 2008-01-10 WO disclosed
WO-2007000778-A2 MODIFIED RELEASE PHARMACEUTICAL COMPOSITIONS ON THE BASIS OF TWO POLYMERS AND PROCESSES THEREOF PANACEA BIOTEC LTD. (IN) 2007-01-04 WO disclosed
US-4470981-A STEROIDS, LOWERING SERUM CHOLESTEROL HESSE ROBERT H 1984-09-11 US disclosed