Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536437 | 0.95 | DGKA (0.60) | TSHRSLC22A6DGKANPC1LMNA | |
| SCHEMBL1389328 | 0.93 | TSHR (0.52) | TSHRSLC22A6DGKANPC1LMNA | |
| SCHEMBL4669422 | 0.92 | TSHR (0.56) | TSHRSLC22A6DGKANPC1LMNA | |
| SCHEMBL586052 | 0.92 | DGKA (0.64) | TSHRSLC22A6DGKALMNANFKB1 | |
| SCHEMBL27343249 | 0.92 | DGKA (0.64) | TSHRSLC22A6DGKALMNANFKB1 | |
| SCHEMBL7172777 | 0.92 | TSHR (0.56) | TSHRSLC22A6DGKANPC1LMNA | |
| SCHEMBL3503544 | 0.92 | DGKA (0.64) | TSHRSLC22A6DGKALMNANFKB1 | |
| SCHEMBL4401743 | 0.92 | DGKA (0.64) | TSHRSLC22A6DGKALMNANFKB1 | |
| SCHEMBL3503100 | 0.92 | DGKA (0.64) | TSHRSLC22A6DGKALMNANFKB1 | |
| SCHEMBL27861896 | 0.92 | TSHR (0.56) | TSHRSLC22A6DGKANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150119-B1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX INC (US) | 2018-04-11 | — | — | EP | claimed |
| US-20100129417-A1 | Dihydroxybenzoate Polymers and Uses Thereof | MEDTRONIC, INC. | 2010-05-27 | — | — | US | claimed |
| EP-2150119-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA INC. (US) | 2010-02-10 | — | — | EP | claimed |
| WO-2008137807-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA, INC. (US) | 2008-11-13 | — | — | WO | claimed |
| EP-2150119-B1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX INC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9491966-B2 | Dihydroxybenzoate polymers and uses thereof | TYRX, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-8084625-B2 | Crosslinking agent, crosslinking method, method of controlling gene expression, and method of examining gene function | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-8084625-B2 | Crosslinking agent, crosslinking method, method of controlling gene expression, and method of examining gene function | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-8084625-B2 | Crosslinking agent, crosslinking method, method of controlling gene expression, and method of examining gene function | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20100129417-A1 | Dihydroxybenzoate Polymers and Uses Thereof | MEDTRONIC, INC. | 2010-05-27 | — | — | US | disclosed |
| EP-2150119-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA INC. (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20090023140-A1 | CROSSLINKING AGENT, CROSSLINKING METHOD, METHOD OF CONTROLLING GENE EXPRESSION, AND METHOD OF EXAMINING GENE FUNCTION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-22 | — | — | US | disclosed |
| US-20090023140-A1 | CROSSLINKING AGENT, CROSSLINKING METHOD, METHOD OF CONTROLLING GENE EXPRESSION, AND METHOD OF EXAMINING GENE FUNCTION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-22 | — | — | US | disclosed |
| US-20090023140-A1 | CROSSLINKING AGENT, CROSSLINKING METHOD, METHOD OF CONTROLLING GENE EXPRESSION, AND METHOD OF EXAMINING GENE FUNCTION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-22 | — | — | US | disclosed |
| WO-2008137807-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023140-A1 | CROSSLINKING AGENT, CROSSLINKING METHOD, METHOD OF CONTROLLING GENE EXPRESSION, AND METHOD OF EXAMINING GENE FUNCTION | DCLRE1A, RNGTT, NSUN2 | TSHR 3242/4885SLC22A6 4288/4885DGKA 1451/4885 |
| US-20100129417-A1 | Dihydroxybenzoate Polymers and Uses Thereof | DDT, QDPR, HPD | TSHR 4753/4885SLC22A6 1704/4885DGKA 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.