Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314196 | 0.87 | LMNA (0.46) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7887703 | 0.83 | MAPK8 (0.56) | LMNAALDH1A1MAPK8KDM4EGAA | |
| SCHEMBL27834431 | 0.83 | LMNA (0.52) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15693830 | 0.83 | ICMT (0.44) | ALDH1A1RAB9ASMN1; SMN2TSHRKDM4E | |
| SCHEMBL21771864 | 0.83 | MAPT (0.44) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21771913 | 0.81 | AKT1 (0.60) | LMNAALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL3957122 | 0.81 | HSD17B10 (0.56) | LMNAALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL21771873 | 0.80 | L3MBTL1 (0.42) | ALDH1A1RAB9ATSHRKDM4EGAA | |
| SCHEMBL8197650 | 0.80 | LMNA (0.48) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6696944 | 0.79 | LMNA (0.47) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136421-B2 | Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof | BEIJING LIHE TECHNOLOGY LTD (CN) | 2021-10-05 | — | — | US | disclosed |
| CN-108517022-B | Solid catalyst component for olefin polymerization, catalyst and application thereof | 北京利和知信科技有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-108517021-B | Solid catalyst component suitable for producing polymer with wide molecular weight distribution, catalyst and application thereof | 北京利和知信科技有限公司 | 2020-10-27 | — | — | CN | disclosed |
| US-20200071430-A1 | SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2020-03-05 | — | — | US | disclosed |