Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 16/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.42 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21425772 | 0.85 | CSF1R (0.42) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL21426311 | 0.82 | CSF1R (0.59) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL30086983 | 0.82 | CSF1R (0.59) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL21772047 | 0.80 | CSF1R (0.52) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL30890848 | 0.80 | CSF1R (0.52) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL16028609 | 0.80 | CSF1R (0.52) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL16028789 | 0.79 | HTR6 (0.43) | CSF1RPDGFRAKITFLT3KDR | |
| SCHEMBL25248350 | 0.78 | TGFBR1 (0.39) | CSF1RPDGFRAKITPDGFRB | |
| SCHEMBL16029255 | 0.78 | TGFBR1 (0.39) | — | |
| SCHEMBL30890883 | 0.78 | TGFBR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149021-B2 | N-(azaaryl)cyclolactam-1-carboxamide derivative, preparation method therefor, and use thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-20200071302-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071302-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | CSF1R, CSF3R, FAR1 | CSF1R 1/4885PDGFRA 586/4885KIT 195/4885 |
| US-11149021-B2 | N-(azaaryl)cyclolactam-1-carboxamide derivative, preparation method therefor, and use thereof | CSF1R, CSF3R, FAR1 | CSF1R 1/4885PDGFRA 586/4885KIT 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.