Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29198878 | 0.81 | TPMT (0.67) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL21772126 | 0.81 | TSHR (0.42) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL30079619 | 0.80 | TPMT (0.51) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL30079547 | 0.75 | CA12 (0.47) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29198761 | 0.75 | CA12 (0.47) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL21373264 | 0.74 | GSK3B (0.52) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL26810030 | 0.74 | TPMT (0.51) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL6507928 | 0.74 | ALDH1A1 (0.58) | HTTTSHRAPOBEC3AAPOBEC3GTPMT | |
| Hydrochloric Acid SCHEMBL5378576 | 0.73 | GSK3B (0.52) | HTTTSHRAPOBEC3AAPOBEC3GMAPT | |
| Hydrochloric Acid SCHEMBL5419382 | 0.73 | ALDH1A1 (0.57) | HTTTSHRAPOBEC3AAPOBEC3GTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643714-B1 | 4,5-DISUBSTITUTED-1-HYDRO-PYRROLE(2,3-F)QUINOLONE-2,7,9-TRICARBOXYLATE COMPOUND AND APPLICATIONS | SHANDONG YUANLITAI MEDICAL TECH CO LTD (CN) | 2024-01-10 | — | — | EP | disclosed |
| US-10807979-B2 | 4,5-disubstituted-1H-pyrrolo(2,3-f)quinolin-2,7,9-tricarboxylate compound and use thereof | SHANGDONG CAMASY BIOTECHNOLOGY CO., LTD. (CN) | 2020-10-20 | — | — | US | disclosed |
| EP-3643714-A1 | 4,5-DISUBSTITUTED-1-HYDRO-PYRROLE(2,3-F)QUINOLONE-2,7,9-TRICARBOXYLATE COMPOUND AND APPLICATIONS | Wang, Jinglin (CN) | 2020-04-29 | — | — | EP | disclosed |
| US-20200071319-A1 | 4,5-DISUBSTITUTED-1H-PYRROLO(2,3-F)QUINOLIN-2,7,9-TRICARBOXYLATE COMPOUND AND USE THEREOF | WANG, Jinglin (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807979-B2 | 4,5-disubstituted-1H-pyrrolo(2,3-f)quinolin-2,7,9-tricarboxylate compound and use thereof | MT-ND4L, GLUL, SDHA | HTT 1295/4885TSHR 3643/4885APOBEC3A 3323/4885 |
| US-20200071319-A1 | 4,5-DISUBSTITUTED-1H-PYRROLO(2,3-F)QUINOLIN-2,7,9-TRICARBOXYLATE COMPOUND AND USE THEREOF | MT-ND4L, GLUL, SDHA | HTT 1295/4885TSHR 3643/4885APOBEC3A 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.