Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 10/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957633 | 0.85 | HSD17B1 (0.51) | MEN1KMT2AHTTL3MBTL1PTGES | |
| SCHEMBL2173709 | 0.85 | MEN1 (0.52) | MEN1KMT2AHTTL3MBTL1TRIM24 | |
| SCHEMBL1749307 | 0.84 | MEN1 (0.42) | MEN1KMT2AHTTL3MBTL1BCHE | |
| SCHEMBL942814 | 0.83 | MEN1 (0.51) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL3948563 | 0.83 | AOC3 (0.57) | BCHEAOC3TRIM24TRIM33ABHD6 | |
| SCHEMBL6255368 | 0.82 | PTGES (0.48) | BCHEPTGESAOC3TRIM24TRIM33 | |
| SCHEMBL6184553 | 0.82 | PTGES (0.52) | BCHEPTGESAOC3TRIM24TRIM33 | |
| SCHEMBL2952041 | 0.81 | HSD17B1 (0.52) | MEN1KMT2AHTTL3MBTL1PTGES | |
| SCHEMBL1362748 | 0.80 | TRIM24 (0.41) | MEN1KMT2AHTTL3MBTL1PTGES | |
| SCHEMBL1315024 | 0.78 | TAAR1 (0.51) | BCHEAOC3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |