Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21095863 | 0.82 | CYP1A2 (0.43) | CYP1A2CYP2D6KCNN4KIF11KMT2A | |
| SCHEMBL3812105 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL8868519 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL8868505 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL5899999 | 0.79 | ALDH1A1 (0.39) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL27413509 | 0.78 | MAPK1 (0.39) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL21895765 | 0.77 | POLB (0.40) | CYP1A2CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL3439362 | 0.75 | KMT2A (0.42) | CYP1A2CYP2D6KCNN4CHRM2CHRM1 | |
| SCHEMBL16062155 | 0.74 | ALDH1A1 (0.41) | CYP1A2CYP2D6KCNN4KIF11CYP2C19 | |
| SCHEMBL4367368 | 0.73 | MAPK1 (0.42) | CYP1A2CYP2D6KCNN4KIF11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166163-A1 | SUBSTITUTED FUROPYRIMIDINES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166163-A1 | SUBSTITUTED FUROPYRIMIDINES AND USE THEREOF | DPYD, TPMT, TYMP | CYP1A2 154/4885CYP2D6 74/4885KCNN4 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.