Sugi Predict

Sugi Predict / Compounds / SCHEMBL4367368

SCHEMBL4367368

SCHEMBL4367368

CC(C)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.42
▸ KIF11 P52732 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ CYP2D6 P10635 2/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ KCNN4 O15554 4/20 0.37
▸ TSHR P16473 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TAAR1 Q96RJ0 1/20 0.34
▸ ESR1 P03372 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17173364 0.86 CA4 (0.46) KIF11ALDH1A1KMT2A
SCHEMBL21562153 0.86 CA4 (0.46) KIF11ALDH1A1KMT2A
SCHEMBL16062155 0.81 ALDH1A1 (0.41) MAPK1KIF11ALDH1A1ALOX15CYP2D6
SCHEMBL8813285 0.81 MAPK1 (0.39) MAPK1KIF11ALDH1A1ALOX15CYP2D6
SCHEMBL11154095 0.80 MAPK1 (0.42) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL3416867 0.79 IRAK4 (0.38) ALDH1A1GAANPSR1
SCHEMBL13641887 0.78 MAPK1 (0.46) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL7153634 0.78 MAPK1 (0.58) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL5899999 0.78 ALDH1A1 (0.39) MAPK1KIF11ALDH1A1ALOX15CYP2D6
SCHEMBL8812383 0.78 MAPK1 (0.41) MAPK1KIF11ALDH1A1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4284851-A1 SILANE-TERMINATED POLYMERS MERZ + BENTELI AG (CH) 2023-12-06 — — EP claimed
WO-2022162106-A1 SILANE-TERMINATED POLYMERS MERZ + BENTELI AG (CH) 2022-08-04 — — WO claimed
US-20230242571-A1 SILICON CONTAINING MODIFIED NUCLEOTIDE ANALOGS FIRST-CITIZENS BANK & TRUST COMPANY 2023-08-03 — — US disclosed
US-20230242571-A1 SILICON CONTAINING MODIFIED NUCLEOTIDE ANALOGS FIRST-CITIZENS BANK & TRUST COMPANY 2023-08-03 — — US disclosed
WO-2023107673-A2 CLEAVABLE DISULFIDE LINKERS AND USES THEREOF Singular Genomics Systems, Inc. (US) 2023-06-15 — — WO disclosed
US-20230160001-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-05-25 — — US disclosed
US-20230160001-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-05-25 — — US disclosed
US-20230119408-A1 NUCLEOTIDE ANALOGS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-04-20 — — US disclosed
US-20230002436-A1 MODIFIED NUCLEOTIDES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-01-05 — — US disclosed
US-11535754-B2 Silicon containing detectable compounds and uses thereof Singular Genomics Systems, Inc. (US) 2022-12-27 — — US disclosed
US-11174281-B1 Modified nucleotides and uses thereof Singular Genomics Systems, Inc. (US) 2021-11-16 — — US disclosed
WO-2021226327-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF Singular Genomics Systems, Inc. (US) 2021-11-11 — — WO disclosed
EP-2749566-B1 SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE AIST (JP) 2018-05-09 — — EP disclosed
US-9428809-B2 Solid-phase carrier for aminated oligonucleotide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-08-30 — — US disclosed
US-20140187724-A1 SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2014-07-03 — — US disclosed
EP-2749566-A1 SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE National Institute of Advanced Industrial Science And Technology (JP) 2014-07-02 — — EP disclosed
EP-1908829-B1 OLIGONUCLEOTIDE PROBE NAT INST OF ADVANCED IND SCIEN (JP) 2014-01-08 — — EP disclosed
US-7491857-B2 Oligonucleotide probe NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2009-02-17 — — US disclosed
US-20080227968-A1 Oligonucleotide Probe NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-18 — — US disclosed
EP-1908829-A1 OLIGONUCLEOTIDE PROBE National Institute of Advanced Industrial Science and Technology (JP) 2008-04-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119408-A1 NUCLEOTIDE ANALOGS AND USES THEREOF NUDT1, PNP, NT5C2 MAPK1 4725/4885KIF11 4103/4885ALDH1A1 1275/4885
US-20230002436-A1 MODIFIED NUCLEOTIDES AND USES THEREOF NUDT1, RNMT, ADAR MAPK1 4820/4885KIF11 3775/4885ALDH1A1 1149/4885
US-11174281-B1 Modified nucleotides and uses thereof NUDT1, RNMT, ADAR MAPK1 4820/4885KIF11 3775/4885ALDH1A1 1149/4885
US-20230242571-A1 SILICON CONTAINING MODIFIED NUCLEOTIDE ANALOGS NSUN2, DCLRE1A, POLI MAPK1 3446/4885KIF11 1184/4885ALDH1A1 4239/4885
US-20080227968-A1 Oligonucleotide Probe APEX1, RNGTT, RNASEH1 MAPK1 2022/4885KIF11 3783/4885ALDH1A1 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.