SCHEMBL2177419

SCHEMBL2177419

O=C(ON1C(=O)c2ccccc2C1=O)ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 1/20 0.50
GAA P10253 1/20 0.48
KMT2A Q03164 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
CA12 O43570 2/20 0.45
CA9 Q16790 2/20 0.45
MEN1 O00255 2/20 0.42
VDR P11473 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
SCN2A Q99250 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4355574 0.88 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9GAAMAPT
SCHEMBL426217 0.86 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL13479811 0.85 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL9276203 0.84 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL12471113 0.83 L3MBTL1 (0.48) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL597194 0.83 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL2177071 0.83 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL859822 0.83 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL22665002 0.83 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9GAAKMT2A
SCHEMBL29838651 0.83 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061368-B Novel fluorescent ink and preparation method and application thereof 厦门大学 2021-12-28 CN claimed
JP-62072724-A None JP disclosed
WO-2023125935-A1 BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2023-07-06 WO disclosed
CN-114026173-B Fiber-reinforced flame retardant poly (ester-carbonate) compositions 高新特殊工程塑料全球技术有限公司 2023-06-09 CN disclosed
CN-115449227-A Thermoplastic composition, article thereof and method of forming 高新特殊工程塑料全球技术有限公司 2022-12-09 CN disclosed
CN-115038740-A Poly (carbonate-siloxane) compositions with improved appearance 高新特殊工程塑料全球技术有限公司 2022-09-09 CN disclosed
CN-114026173-A Fiber reinforced flame retardant poly (ester-carbonate) compositions 高新特殊工程塑料全球技术有限公司 2022-02-08 CN disclosed
CN-111410830-A 3D printing heat-resistant supporting material 沙特基础工业全球技术有限公司 2020-07-14 CN disclosed
CN-111315803-A Process for making thermoplastic polymer particles, thermoplastic polymer particles made thereby, and articles made therefrom 沙特基础工业全球技术有限公司 2020-06-19 CN disclosed
CN-111205341-A Preparation method of prazolmitrin key intermediate 山东安信制药有限公司 2020-05-29 CN disclosed
EP-0175363-B1 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1990-01-17 EP disclosed
EP-0346684-A1 Substituted 3-aminosydnonimines, method for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1989-12-20 EP disclosed
EP-0346694-A1 Substituted 3-Aminosydnone imines, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1989-12-20 EP disclosed
EP-0327808-A1 Substituted 3-aminosydnonimines, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1989-08-16 EP disclosed
US-4845091-A HYPOTENSIVE AGENTS, VASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0312773-A2 Substituted 3-aminosydnonimines, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1989-04-26 EP disclosed
US-4816454-A CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
JP-S6272724-A PRODUCTION OF POLYAMIDE ASAHI CHEM IND CO LTD 1987-04-03 JP disclosed
EP-0210474-A1 Substituted 3-amino-sydnone imines, method for their preparation, their use and pharmaceutical compositions containing these compounds CASSELLA Aktiengesellschaft (DE) 1987-02-04 EP disclosed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP disclosed