Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177419 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP2C9SCN2A | |
| SCHEMBL12471113 | 0.80 | L3MBTL1 (0.48) | ALDH1A1MAPTCYP1A2CYP2C9KDM4E | |
| SCHEMBL597194 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP1A2CYP2C9SCN2A | |
| SCHEMBL859822 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP1A2CYP2C9SCN2A | |
| SCHEMBL29838651 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP1A2CYP2C9SCN2A | |
| SCHEMBL426217 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP2C9SCN2A | |
| SCHEMBL29439746 | 0.79 | LMNA (0.45) | ALDH1A1MAPTCYP1A2CYP2C9GAA | |
| SCHEMBL11711022 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP1A2CYP2C9POLB | |
| SCHEMBL3676819 | 0.79 | LMNA (0.45) | ALDH1A1MAPTCYP1A2CYP2C9GAA | |
| SCHEMBL23534358 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286060-A1 | Degradable polymer article | CIBA CORP. | 2009-11-19 | — | — | US | disclosed |
| US-20090286060-A1 | Degradable polymer article | CIBA CORP. | 2009-11-19 | — | — | US | disclosed |
| US-20090286060-A1 | Degradable polymer article | CIBA CORP. | 2009-11-19 | — | — | US | disclosed |
| WO-2007028731-A1 | A DEGRADABLE POLYMER ARTICLE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-03-15 | — | — | WO | disclosed |