Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180469 | 0.81 | LOX (0.32) | LMNAPTGS2PTGS1 | |
| SCHEMBL2178026 | 0.80 | NR1H2 (0.35) | PTGS2 | |
| SCHEMBL2179886 | 0.75 | ENPP2 (0.31) | PTGS2PTGS1 | |
| SCHEMBL2179000 | 0.75 | PIK3CA (0.33) | PTGS2PTGS1 | |
| SCHEMBL2178152 | 0.73 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL2176609 | 0.73 | PTGS2 (0.33) | LMNAPTGS2LRRK2PTGS1 | |
| SCHEMBL20554194 | 0.73 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL20554278 | 0.73 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL2177759 | 0.70 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL2179380 | 0.70 | PTGS1 (0.31) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | SMN1; SMN2 2625/4885LMNA 1548/4885FYN 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.