SCHEMBL21775400

SCHEMBL21775400

N#CC=C1CN(S(=O)(=O)NC(=O)O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21775417 0.78 CTSK (0.36)
SCHEMBL21775412 0.72 CA1 (0.31)
SCHEMBL873288 0.69
SCHEMBL20527971 0.67 POLB (0.45)
SCHEMBL3194361 0.67 AKR1C3 (0.50)
SCHEMBL23141170 0.67 SCN9A (0.36)
SCHEMBL18975877 0.67 CYP2C9 (0.47)
SCHEMBL20527949 0.64 TSHR (0.36)
SCHEMBL23141199 0.64 USP30 (0.33)
SCHEMBL15018117 0.64 GAA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300891-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME INCYTE CORPORATION 2021-09-30 US disclosed
US-10968200-B2 Salts of an LSD1 inhibitor and processes for preparing the same INCYTE CORPORATION (US) 2021-04-06 US disclosed
WO-2020047198-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME INCYTE CORPORATION (US) 2020-03-05 WO disclosed
US-20200071289-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME WILMINGTON PHARMATECH 2020-03-05 US disclosed