SCHEMBL2552726

SCHEMBL2552726

CC(O)CC(=O)OCC(O)CO

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
DUSP3 P51452 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 1/20 0.53
DGKA P23743 1/20 0.45
PRKCA P17252 4/20 0.44
FAAH O00519 2/20 0.43
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15319570 1.00 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL22300929 0.93 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL19976113 0.93 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL25476040 0.93 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21471879 0.89 PRKCA (0.45) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21471824 0.89 PRKCA (0.45) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL4805747 0.88 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL10415158 0.85 LMNA (0.53) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21775801 0.83 MAPT (0.43) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL21775800 0.83 MAPT (0.43) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3937656-B1 TASTE-MASKING FORMULATION FOR KETONE BODY COMPOUNDS NEUROENERGY VENTURES INC (US) 2025-04-02 EP claimed
US-12225919-B2 Taste-masking formulation for ketone body compounds NEUROENERGY VENTURES, INC. (US) 2025-02-18 US claimed
CN-113543652-B Taste masking formulations for ketone body compounds 神经活力投资公司 2024-07-05 CN claimed
CN-113329992-B Process for the production of hydroxycarboxylic esters based on polyols 凯托利皮克斯治疗有限责任公司 2024-04-30 CN claimed
CN-114008015-B Process for the preparation of polyhydric alcohol esters of hydroxycarboxylic acids, in particular polyglycerol esters 凯托利皮克斯治疗有限责任公司 2024-02-20 CN claimed
EP-3558458-B1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT NEUROENERGY VENTURES INC (US) 2023-10-18 EP claimed
CN-116209696-A Process for preparing polyglycerol esters of 3-hydroxybutyric acid crosslinked with polycarboxylic acids IOI油脂化学品有限责任公司 2023-06-02 CN claimed
US-11638702-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury NeuroEnerygy Ventures, Inc. (US) 2023-05-02 US claimed
CN-110167637-B Use of glycerol 3-hydroxybutyrate for migraine symptom management 神经活力投资公司 2023-03-14 CN claimed
US-20220338510-A2 Taste-Masking Formulation For Ketone Body Compounds NEUROENERGY VENTURES, INC. (US) 2022-10-27 US claimed
WO-2018132189-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY NEUROENERGY VENTURES, INC. (US) 2018-07-19 WO claimed
US-20180193300-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY NEUROENERGY VENTURES, INC. (US) 2018-07-12 US claimed
WO-2018118369-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT NEUROENERGY VENTURES,INC. (US) 2018-06-28 WO claimed
US-20180177753-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT NEUROENERGY VENTURES, INC. (US) 2018-06-28 US claimed
US-9925164-B1 Glyceryl 3-hydroxybutyrates for traumatic brain injury NEUROENERGY VENTURES, INC. (US) 2018-03-27 US claimed
EP-1648952-B1 NUTRITIONAL SUPPLEMENTS AND THERAPEUTIC COMPOSITIONS COMPRISING (R)-3-HYDROXYBUTYRATE DERIVATIVES THE US GOV AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2018-03-07 EP claimed
WO-1995009144-A1 NUTRITIVE WATER SOLUBLE GLYCEROL ESTERS OF HYDROXY BUTYRIC ACID EASTMAN CHEMICAL COMPANY (US) 1995-04-06 WO claimed
US-4701443-A PARENTAL ADMINISTERING BAXTER TRAVENOL LABORATORIES, INC. (US) 1987-10-20 US claimed
EP-0139677-A1 NUTRIENT POLYESTERS BAXTER TRAVENOL LABORATORIES, INC. (US) 1985-05-08 EP claimed
WO-1984003626-A1 NUTRIENT POLYESTERS BAXTER TRAVENOL LAB (US) 1984-09-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180177753-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR MIGRAINE SYMPTOM MANAGEMENT HTR3B, MGLL, HTR3A KDM4E 2988/4885DUSP3 3128/4885MEN1 1094/4885
US-20180193300-A1 GLYCERYL 3-HYDROXYBUTYRATES FOR TRAUMATIC BRAIN INJURY FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885
US-11638702-B2 Glyceryl 3-hydroxybutyrates for traumatic brain injury FABP7, B3GAT3, PYGB KDM4E 3535/4885DUSP3 4584/4885MEN1 3920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.