Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 4/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775898 | 1.00 | SOAT2 (0.51) | SOAT2SOAT1EPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL21774130 | 0.87 | HPGD (0.48) | ALDH1A1L3MBTL1ATMMAPTLMNA | |
| SCHEMBL21774357 | 0.86 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1ATMKMT2ANTRK1 | |
| SCHEMBL25763347 | 0.83 | SOAT2 (0.46) | SOAT2SOAT1ALDH1A1L3MBTL1ATM | |
| SCHEMBL21774356 | 0.83 | SOAT2 (0.46) | SOAT2SOAT1ALDH1A1L3MBTL1ATM | |
| SCHEMBL21774129 | 0.82 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ATMNTRK1MAPT | |
| SCHEMBL21774134 | 0.81 | NTRK1 (0.50) | ALDH1A1L3MBTL1ATMKMT2ANTRK1 | |
| SCHEMBL21753650 | 0.79 | GAA (0.57) | ALDH1A1L3MBTL1ATMKMT2ANTRK1 | |
| SCHEMBL21774368 | 0.79 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMNTRK1MAPT | |
| SCHEMBL21774366 | 0.78 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ATMNTRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | JIANGSU VANGUARD PHARMACEUTICAL CO., LTD. (CN) | 2023-07-04 | — | — | US | disclosed |
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | JIANGSU VANGUARD PHARMACEUTICAL CO., LTD. (CN) | 2023-07-04 | — | — | US | disclosed |
| CN-110857285-B | Substituted pyrazole compound, preparation method, pharmaceutical composition and application thereof | 江苏万高药业股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| WO-2020038279-A1 | SUBSTITUTED PYRAZOLE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 天津谷堆生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | FARS2, GOT2, HADHB | SOAT2 1946/4885SOAT1 2134/4885EPHX2 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.