SCHEMBL1335872

SCHEMBL1335872

Cc1ccc(Nc2ccc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
CYP1A2 P05177 3/20 0.44
LMNA P02545 3/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
PTGS2 P35354 2/20 0.44
AKR1C3 P42330 2/20 0.44
HIF1A Q16665 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
AKR1B10 O60218 1/20 0.44
TRPA1 O75762 1/20 0.44
ABCB11 O95342 1/20 0.44
DHFR P00374 1/20 0.44
MPO P05164 1/20 0.44
CHRM1 P11229 1/20 0.44
AKR1B1 P15121 1/20 0.44
PTGS1 P23219 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21776018 0.84 RAPGEF4 (0.59) KMT2AMEN1LMNARAPGEF4POLB
SCHEMBL18461006 0.80 IDO1 (0.33) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL3700950 0.78 POLB (0.33) CYP1A2POLBMAPTCYP2A6TSHR
SCHEMBL37955 0.77 TSHR (0.45) CYP1A2CYP3A4TDP1TRPA1POLB
SCHEMBL5494672 0.77 TSHR (0.45) CYP1A2CYP3A4TDP1TRPA1POLB
SCHEMBL24246232 0.76 ALDH1A1 (0.34) CYP1A2MAPTCYP2A6TSHRTDP2
Hydrochloric Acid SCHEMBL9630416 0.76 POLB (0.32) CYP1A2TDP1POLBMAPTCYP2A6
SCHEMBL4189645 0.74 RAPGEF4 (0.65) KMT2AMEN1CYP1A2LMNACYP3A4
SCHEMBL16867408 0.74 CYP3A4 (0.50) KMT2AMEN1LMNACYP3A4MAPT
SCHEMBL14567673 0.74 IDO1 (0.39) LMNACYP3A4HIF1ATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797872-B1 SULFIDE SCAVENGERS, METHODS FOR MAKING THEM AND METHODS FOR USING THEM GEN ELECTRIC (US) 2018-02-28 EP claimed
US-9108899-B2 Sulfide scavengers, methods for making and methods for using GENERAL ELECTRIC COMPANY (US) 2015-08-18 US claimed
EP-2797872-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING THEM General Electric Company (US) 2014-11-05 EP claimed
US-8530394-B2 Sterically hindered N-methyl secondary and tertiary amine sulfur scavengers and methods for making and using same CLEARWATER INTERNATIONAL LLC (US) 2013-09-10 US claimed
US-20130172623-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING GENERAL ELECTRIC COMPANY (US) 2013-07-04 US claimed
WO-2013101361-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING THEM GENERAL ELECTRIC COMPANY (US) 2013-07-04 WO claimed
US-20090250659-A1 STERICALLY HINDERED N-METHYL SECONDARY AND TERTIARY AMINE SULFUR SCAVENGERS AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2009-10-08 US claimed
US-20050153846-A1 Sterically hindered N-methylsecondary and tertiary amine sulfur scavengers and methods for making and using same WEATHERFORD/LAMB, INC. 2005-07-14 US claimed
CN-114660896-B Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound 信越化学工业株式会社 2024-06-11 CN disclosed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
EP-2797872-B1 SULFIDE SCAVENGERS, METHODS FOR MAKING THEM AND METHODS FOR USING THEM GEN ELECTRIC (US) 2018-02-28 EP disclosed
US-9440909-B2 Sulfide scavengers, methods for making and methods for using GENERAL ELECTRIC COMPANY (US) 2016-09-13 US disclosed
US-20150299100-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING BL TECHNOLOGIES, INC. 2015-10-22 US disclosed
US-9108899-B2 Sulfide scavengers, methods for making and methods for using GENERAL ELECTRIC COMPANY (US) 2015-08-18 US disclosed
US-8022253-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-09-20 US disclosed
US-20090250659-A1 STERICALLY HINDERED N-METHYL SECONDARY AND TERTIARY AMINE SULFUR SCAVENGERS AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2009-10-08 US disclosed
US-7517447-B2 Sterically hindered N-methylsecondary and tertiary amine sulfur scavengers and methods for making and using same CLEARWATER INTERNATIONAL, LLC (US) 2009-04-14 US disclosed
EP-2008992-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-12-31 EP disclosed
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-01-03 US disclosed
US-20050153846-A1 Sterically hindered N-methylsecondary and tertiary amine sulfur scavengers and methods for making and using same WEATHERFORD/LAMB, INC. 2005-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, PRDM9 KMT2A 139/4885MEN1 2117/4885CYP1A2 507/4885
US-20150299100-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING CBS, TST, GSS KMT2A 3923/4885MEN1 3709/4885CYP1A2 2188/4885
US-20130172623-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING CBS, TST, GSS KMT2A 3923/4885MEN1 3709/4885CYP1A2 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.