Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776958 | 1.00 | FNTA (0.48) | FNTAFNTBKMT2ACRHBPCRHR2 | |
| SCHEMBL23699692 | 0.87 | FNTA (0.61) | FNTAFNTBCRHBPCRHR2ALDH1A1 | |
| SCHEMBL23699693 | 0.87 | FNTA (0.61) | FNTAFNTBCRHBPCRHR2ALDH1A1 | |
| SCHEMBL21794720 | 0.84 | FNTA (0.49) | FNTAFNTBCRHBPCRHR2LMNA | |
| SCHEMBL23712605 | 0.84 | FNTA (0.49) | FNTAFNTBCRHBPCRHR2LMNA | |
| SCHEMBL21794788 | 0.73 | CRHBP (0.51) | CRHBPCRHR2LMNAALDH1A1MMP1 | |
| SCHEMBL1802673 | 0.73 | CRHBP (0.60) | CRHBPCRHR2LMNAALDH1A1 | |
| SCHEMBL28042132 | 0.72 | CRHBP (0.55) | KMT2ACRHBPCRHR2LMNAHPGD | |
| SCHEMBL21794878 | 0.70 | LMNA (0.49) | KMT2ACRHBPCRHR2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL23699686 | 0.70 | PPID (0.47) | FNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843841-A1 | COMPOUNDS FOR THE MODULATION OF CYCLOPHILINS FUNCTION | The University Court Of The University of Edinburgh (GB) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020043831-A1 | COMPOUNDS FOR THE MODULATION OF CYCLOPHILINS FUNCTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-03-05 | — | — | WO | disclosed |