Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | GCK | P35557 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180465 | 0.92 | GCK (0.38) | NAMPTGCKMAPK1 | |
| SCHEMBL2179066 | 0.83 | EGLN2 (0.39) | NAMPTGCKADAMTS4 | |
| SCHEMBL2177767 | 0.81 | GCK (0.39) | GCK | |
| SCHEMBL2180461 | 0.73 | GCK (0.46) | GCK | |
| SCHEMBL2180005 | 0.69 | GCK (0.40) | GCK | |
| SCHEMBL2178527 | 0.68 | GCK (0.35) | GCKMAPK1 | |
| SCHEMBL2179386 | 0.68 | GCK (0.35) | GCKMAPK1 | |
| SCHEMBL2179064 | 0.65 | GCK (0.44) | GCK | |
| SCHEMBL2038418 | 0.64 | KMT2A (0.38) | NAMPTGCKRORC | |
| SCHEMBL2039421 | 0.63 | GCK (0.39) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |