Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179386 | 0.92 | GCK (0.35) | GCKLRRK2MAPK1PTGS2PTGS1 | |
| SCHEMBL2180005 | 0.84 | GCK (0.40) | GCKLRRK2PTGS2PTGS1 | |
| SCHEMBL2178524 | 0.79 | GCK (0.42) | GCKLRRK2 | |
| SCHEMBL2180465 | 0.76 | GCK (0.38) | GCKLRRK2MAPK1 | |
| SCHEMBL2044900 | 0.75 | GCK (0.37) | GCKPTGS2PTGS1 | |
| SCHEMBL2179383 | 0.72 | GCK (0.41) | GCKLRRK2 | |
| SCHEMBL2178179 | 0.72 | ALDH1A1 (0.34) | GCK | |
| SCHEMBL2177771 | 0.68 | NAMPT (0.33) | GCKMAPK1 | |
| SCHEMBL2178449 | 0.68 | PIK3C3 (0.37) | GCK | |
| SCHEMBL2038418 | 0.67 | KMT2A (0.38) | GCKLRRK2MTORATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |