Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177771 | 0.92 | NAMPT (0.33) | GCKMAPK1NAMPT | |
| SCHEMBL2179066 | 0.84 | EGLN2 (0.39) | GCKNAMPT | |
| SCHEMBL2180461 | 0.80 | GCK (0.46) | GCKLRRK2 | |
| SCHEMBL2180005 | 0.77 | GCK (0.40) | GCKLRRK2 | |
| SCHEMBL2178527 | 0.76 | GCK (0.35) | GCKMAPK1LRRK2 | |
| SCHEMBL2179386 | 0.75 | GCK (0.35) | GCKMAPK1LRRK2 | |
| SCHEMBL2177767 | 0.73 | GCK (0.39) | GCK | |
| SCHEMBL2038418 | 0.71 | KMT2A (0.38) | GCKLRRK2NAMPT | |
| SCHEMBL2044900 | 0.70 | GCK (0.37) | GCK | |
| SCHEMBL2179064 | 0.66 | GCK (0.44) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |