Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777928 | 0.95 | PTGS1 (0.60) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2622 | 0.95 | PTGS1 (0.60) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2521154 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2524419 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL5763087 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Hydrochloric Acid SCHEMBL14053301 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2288880 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL20607658 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Water SCHEMBL162527 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL5760499 | 0.91 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000219-B1 | MACROCYCLIC POLYETHER COMPLEXES AND A PROCESS FOR THE ISOLATION OF MACROCYCLIC POLYETHERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-09-23 | — | — | EP | claimed |
| US-4199513-A | SAFER METHOD OF ISOLATING CROWN ETHERS | SHELL OIL COMPANY (US) | 1980-04-22 | — | — | US | claimed |
| EP-0000219-A1 | Macrocyclic polyether complexes and a process for the isolation of macrocyclic polyethers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-01-10 | — | — | EP | claimed |
| US-12129239-B2 | Method for producing methylene disulfonate compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2024-10-29 | — | — | US | disclosed |
| EP-4006020-B1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2024-09-25 | — | — | EP | disclosed |
| CN-114144407-B | Process for producing cyclic disulfonate compound | 住友精化株式会社 | 2024-02-13 | — | — | CN | disclosed |
| US-11802119-B2 | Method for producing cyclic disulfonic acid ester compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2023-10-31 | — | — | US | disclosed |
| US-20220251060-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220251059-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2022-08-11 | — | — | US | disclosed |
| EP-4006020-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2022-06-01 | — | — | EP | disclosed |
| EP-4006019-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021015219-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | 住友精化株式会社 | 2021-01-28 | — | — | WO | disclosed |
| EP-2610250-B1 | METHOD FOR PRODUCING A METHYLENE DISULFONATE COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-8501966-B2 | Method for producing a methylene disulfonate compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-08-06 | — | — | US | disclosed |
| EP-2610250-A1 | METHOD FOR PRODUCING A METHYLENE DISULFONATE COMPOUND | Sumitomo Seika Chemicals Co. Ltd. (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130137881-A1 | METHOD FOR PRODUCING A METHYLENE DISULFONATE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| CN-103080099-A | Method for producing a methylene disulfonate compound | SUMITOMO SEIKA CHEMICALS | 2013-05-01 | — | — | CN | disclosed |
| EP-0000219-B1 | MACROCYCLIC POLYETHER COMPLEXES AND A PROCESS FOR THE ISOLATION OF MACROCYCLIC POLYETHERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-09-23 | — | — | EP | disclosed |
| US-4199513-A | SAFER METHOD OF ISOLATING CROWN ETHERS | SHELL OIL COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| EP-0000219-A1 | Macrocyclic polyether complexes and a process for the isolation of macrocyclic polyethers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129239-B2 | Method for producing methylene disulfonate compound | TST, MPST, SQOR | PTGS1 1297/4885PDE4A 4430/4885LMNA 4690/4885 |
| US-20220251060-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | STS, TST, SCLY | PTGS1 1684/4885PDE4A 3360/4885LMNA 4732/4885 |
| US-20220251059-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | TST, MPST, SQOR | PTGS1 1297/4885PDE4A 4430/4885LMNA 4690/4885 |
| US-20130137881-A1 | METHOD FOR PRODUCING A METHYLENE DISULFONATE COMPOUND | DHPS, ADH7, MPST | PTGS1 1332/4885PDE4A 4339/4885LMNA 4415/4885 |
| US-11802119-B2 | Method for producing cyclic disulfonic acid ester compound | STS, TST, SCLY | PTGS1 1684/4885PDE4A 3360/4885LMNA 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.