Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854920 | 0.86 | AHR (0.53) | AHRCYP3A4TSHR | |
| SCHEMBL854874 | 0.86 | AHR (0.39) | AHRPTGS1TACR1NFE2L2 | |
| SCHEMBL15741495 | 0.80 | AHR (0.48) | AHRNOTUMRAPGEF4MAOAMAOB | |
| SCHEMBL13228707 | 0.80 | AHR (0.48) | AHRNOTUMRAPGEF4MAOAMAOB | |
| SCHEMBL16638194 | 0.77 | AHR (0.50) | AHRNOTUMRAPGEF4PTGS1MAOA | |
| SCHEMBL256046 | 0.77 | AHR (0.50) | AHRNOTUMRAPGEF4SLC13A3NFE2L2 | |
| SCHEMBL29769014 | 0.76 | AHR (0.48) | AHRNOTUMRAPGEF4MAOAMAOB | |
| SCHEMBL630462 | 0.76 | AHR (0.48) | AHRNOTUMRAPGEF4MAOAMAOB | |
| SCHEMBL16957386 | 0.76 | AHR (0.48) | AHRNOTUMRAPGEF4PTGS1MAOA | |
| SCHEMBL21314067 | 0.75 | AHR (0.49) | AHRPTGS1MAOAMAOBSLC13A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |