Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177901 | 0.86 | AHR (0.55) | AHRTSHRCYP3A4 | |
| SCHEMBL855775 | 0.79 | ALDH1A1 (0.36) | AHRCYP3A4 | |
| SCHEMBL3973844 | 0.77 | AHR (0.33) | AHR | |
| SCHEMBL9227835 | 0.76 | AHR (0.48) | AHR | |
| SCHEMBL8438859 | 0.75 | AHR (0.47) | AHRTSHRTP53CYP3A4 | |
| SCHEMBL854597 | 0.73 | PTGS1 (0.43) | — | |
| SCHEMBL854874 | 0.71 | AHR (0.39) | AHR | |
| SCHEMBL854913 | 0.71 | APP (0.33) | — | |
| SCHEMBL2012796 | 0.71 | SLC22A12 (0.35) | AHR | |
| SCHEMBL6464457 | 0.70 | AHR (1.00) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| EP-2331515-A1 | INSCETICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2238132-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| EP-2230913-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| EP-2205574-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-07-14 | — | — | EP | disclosed |
| WO-2010020521-A1 | INSCETICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009077197-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-25 | — | — | WO | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009049846-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| EP-1965645-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007070606-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |