Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177901 | 0.86 | AHR (0.55) | AHRPTGS1NFE2L2TACR1 | |
| SCHEMBL17147517 | 0.82 | NFE2L2 (0.38) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL3998676 | 0.79 | NFE2L2 (0.61) | NFE2L2FBP1 | |
| SCHEMBL13790220 | 0.78 | PTGS1 (0.61) | AHRPTGS1NFE2L2IDO1TDO2 | |
| SCHEMBL16829667 | 0.76 | NFE2L2 (0.40) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL16829670 | 0.76 | NFE2L2 (0.40) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL13243702 | 0.76 | NFE2L2 (0.40) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL1044653 | 0.76 | AHR (0.39) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL347778 | 0.75 | CES2 (0.41) | AHRPTGS1CES2RPS6KA3JAK3 | |
| SCHEMBL15741510 | 0.75 | CES2 (0.41) | AHRPTGS1CES2RPS6KA3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2238132-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |