Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211665 | 0.82 | AHR (0.46) | AHRRAPGEF4DDR1PPARGPPARD | |
| SCHEMBL256044 | 0.81 | AHR (0.48) | AHR | |
| SCHEMBL20076864 | 0.78 | AHR (0.61) | AHRNFE2L2 | |
| SCHEMBL2177901 | 0.77 | AHR (0.55) | AHRRAPGEF4NOTUMSLC13A3NFE2L2 | |
| SCHEMBL257116 | 0.77 | AHR (0.36) | AHRRAPGEF4 | |
| SCHEMBL16638194 | 0.76 | AHR (0.50) | AHRRAPGEF4NOTUMNFE2L2 | |
| SCHEMBL256704 | 0.74 | NFE2L2 (0.60) | PPARGPPARANFE2L2 | |
| SCHEMBL27298505 | 0.74 | NFE2L2 (0.60) | PPARGPPARANFE2L2 | |
| SCHEMBL14416283 | 0.74 | NFE2L2 (0.60) | PPARGPPARANFE2L2 | |
| SCHEMBL17655770 | 0.73 | TP53 (0.44) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |