SCHEMBL21779271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18398712	0.84	HDAC3 (0.57)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL18398687	0.80	KMT2A (0.58)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL18181353	0.80	HDAC1 (0.49)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL9908323	0.77	CYP11B1 (0.48)	MEN1KMT2ACYP3A4CYP2D6CYP2C9
	SCHEMBL13005132	0.77	CYP11B1 (0.48)	MEN1KMT2ACYP3A4CYP2D6CYP2C9
	SCHEMBL3352898	0.77	CYP11B1 (0.48)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL18398693	0.77	ALDH1A1 (0.55)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL18398696	0.77	HDAC1 (0.53)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL17165073	0.77	HDAC1 (1.00)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL17165076	0.77	HDAC1 (1.00)	HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.