Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752421 | 0.84 | HTR1A (0.48) | HTR1ADRD2DRD3 | |
| SCHEMBL4540858 | 0.84 | HTR1A (0.48) | HTR1ADRD2DRD3 | |
| SCHEMBL27714841 | 0.83 | HTR1A (0.47) | HTR1ADRD2DRD3 | |
| SCHEMBL2406116 | 0.82 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL15688078 | 0.82 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL324930 | 0.82 | DRD2 (0.60) | HTR1ADRD2DRD3 | |
| SCHEMBL12696027 | 0.82 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL15793169 | 0.82 | HTR1A (0.49) | HTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL15688231 | 0.81 | HTR1A (0.45) | HTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL15687944 | 0.81 | HTR1A (0.45) | HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577361-B2 | Dopamine D3 receptor antagonists having a morpholine moiety | INDIVIOR UK LIMITED (GB) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577361-B2 | Dopamine D3 receptor antagonists having a morpholine moiety | DRD3, DRD2, SLC6A3 | HTR1A 73/4885DRD2 2/4885DRD3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.