Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718668 | 0.85 | CHRNB2 (0.33) | CHRNB2CHRNA4HCAR2MAPK1ADORA2B | |
| SCHEMBL23260180 | 0.79 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL20272980 | 0.79 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL5700554 | 0.79 | HCAR2 (0.39) | CHRNB2CHRNA4HCAR2HDAC8ADORA2B | |
| SCHEMBL20832746 | 0.78 | LMNA (0.41) | CHRNB2CHRNA4HCAR2LMNADYRK1A | |
| SCHEMBL15157880 | 0.78 | SLC6A4 (0.36) | CHRNB2CHRNA4HCAR2SCN10A | |
| SCHEMBL19380148 | 0.78 | HCAR2 (0.35) | HCAR2ALDH1A1GAAUSP2PKM | |
| SCHEMBL7644300 | 0.76 | TSHR (0.40) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL10289777 | 0.76 | TSHR (0.40) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL9178609 | 0.76 | ALDH1A1 (0.39) | ALDH1A1GAAUSP2PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |