Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903306 | 0.76 | CA12 (0.43) | CA12CA1CA2CA9TSHR | |
| SCHEMBL682249 | 0.76 | CA12 (0.46) | CA12CA1CA2CA9TSHR | |
| SCHEMBL25934899 | 0.73 | CA12 (0.45) | CA12CA1CA2CA9TSHR | |
| SCHEMBL24634118 | 0.73 | KEAP1 (0.44) | CA12CA1CA2CA9TSHR | |
| SCHEMBL10409514 | 0.71 | CA12 (0.42) | CA12CA1CA2CA9TSHR | |
| SCHEMBL22456024 | 0.71 | ALDH1A1 (0.46) | CA12CA1CA2CA9TSHR | |
| SCHEMBL23155982 | 0.71 | CA12 (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL28927539 | 0.71 | ALDH1A1 (0.51) | CA12CA1CA2CA9TSHR | |
| SCHEMBL30394130 | 0.70 | GAA (0.49) | CA12CA1CA2CA9TSHR | |
| SCHEMBL7277448 | 0.70 | GAA (0.46) | TSHRTDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |