Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181698 | 0.87 | ALDH1A1 (0.50) | GAATSHRMAPTTDP1SMN1; SMN2 | |
| SCHEMBL30394130 | 0.83 | GAA (0.49) | GAATSHRMAPTTDP1SMN1; SMN2 | |
| SCHEMBL8843457 | 0.78 | GAA (0.41) | GAATSHRMAPTTDP1SMN1; SMN2 | |
| SCHEMBL10448449 | 0.77 | CNR2 (0.52) | GAATSHRMAPTTDP1SMN1; SMN2 | |
| SCHEMBL12310327 | 0.77 | TSHR (0.58) | GAATSHRMAPTTDP1MMP3 | |
| SCHEMBL7277453 | 0.77 | TSHR (0.58) | GAATSHRMAPTTDP1MMP3 | |
| SCHEMBL7287015 | 0.76 | TACR2 (0.54) | ALDH1A1LMNA | |
| SCHEMBL28927539 | 0.75 | ALDH1A1 (0.51) | TSHRTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27560979 | 0.74 | MMP9 (0.52) | TSHRMAPTTDP1MMP3MMP9 | |
| SCHEMBL10266645 | 0.74 | ALDH1A1 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |