Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161654 | 1.00 | GRM2 (0.36) | GRM2THRATHRBSMN1; SMN2HTT | |
| SCHEMBL12239930 | 0.90 | SLC22A2 (0.41) | GRM2THRATHRBSMN1; SMN2HTT | |
| SCHEMBL2296155 | 0.90 | SLC22A2 (0.41) | GRM2THRATHRBSMN1; SMN2HTT | |
| SCHEMBL26727074 | 0.89 | THRA (0.33) | GRM2THRATHRBSMN1; SMN2HTT | |
| SCHEMBL24969604 | 0.86 | SLC22A2 (0.39) | GRM2GLRA1LMNAS1PR5SLC22A2 | |
| SCHEMBL24969606 | 0.84 | SLC22A2 (0.41) | GRM2THRBHTTMEN1ALDH1A1 | |
| SCHEMBL2160801 | 0.82 | HTT (0.42) | GRM2SMN1; SMN2HTTMEN1ALDH1A1 | |
| SCHEMBL21780155 | 0.82 | HTT (0.42) | GRM2SMN1; SMN2HTTMEN1ALDH1A1 | |
| SCHEMBL12263528 | 0.82 | THRA (0.32) | THRATHRBALDH1A1SLC22A2 | |
| SCHEMBL26727070 | 0.80 | GRM2 (0.33) | GRM2THRATHRBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617194-A1 | PROCESSES AND INTERMEDIATES FOR CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS | VIIV Healthcare Company (US) | 2020-03-04 | — | — | EP | disclosed |