Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.58 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23351380 | 0.83 | HSP90AA1 (0.62) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21780055 | 0.83 | TRAP1 (0.58) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL382768 | 0.81 | HSP90AA1 (1.00) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL382173 | 0.81 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL3455489 | 0.79 | HPGD (0.65) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4511791 | 0.78 | HSP90AA1 (0.60) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4279383 | 0.78 | HPGD (0.73) | HPGDALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL30277860 | 0.78 | HPGD (0.73) | HPGDALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL13117434 | 0.76 | HPGD (0.60) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12459664 | 0.76 | CA1 (0.70) | HPGDHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
| EP-3617186-A1 | FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | VAPB, VAPA, SLC28A1 | HPGD 1736/4885HSP90AA1 2419/4885HSP90AB1 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.