Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 11/20 | 0.58 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780096 | 0.83 | HPGD (0.67) | TRAP1HSP90B1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21780058 | 0.76 | AOC2 (0.41) | TRAP1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL21780057 | 0.76 | AOC2 (0.41) | TRAP1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL3412333 | 0.75 | GRM5 (0.54) | TRAP1HSP90B1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27153378 | 0.74 | TRAP1 (0.82) | TRAP1HSP90B1HSP90AA1HSP90AB1 | |
| SCHEMBL27146853 | 0.74 | TRAP1 (1.00) | TRAP1HSP90B1HSP90AA1HSP90AB1 | |
| SCHEMBL4512420 | 0.73 | NOTUM (0.61) | TRAP1ALDH1A1HPGDSMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL21768048 | 0.72 | AOC2 (0.38) | TRAP1ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL21768123 | 0.72 | AOC2 (0.38) | TRAP1ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3416230 | 0.71 | GRM5 (0.48) | TRAP1ALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
| EP-3617186-A1 | FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | VAPB, VAPA, SLC28A1 | TRAP1 1576/4885HSP90B1 1901/4885ALDH1A1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.