Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26337498 | 0.78 | GBA1 (0.42) | MEN1KMT2ANPY5ROPRM1OPRL1 | |
| SCHEMBL21768427 | 0.75 | MAPK1 (0.51) | MEN1KMT2ANPY5ROPRM1OPRL1 | |
| SCHEMBL19105595 | 0.74 | MAPK1 (0.37) | MEN1KMT2ANPY5ROPRM1OPRL1 | |
| SCHEMBL25559304 | 0.73 | MEN1 (0.46) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL22517477 | 0.72 | GBA1 (0.50) | KDM4E | |
| SCHEMBL25505874 | 0.69 | LMNA (0.44) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13165357 | 0.69 | GBA1 (0.39) | MEN1KMT2ANPY5RHSD17B10PDE10A | |
| SCHEMBL12186160 | 0.69 | LMNA (0.42) | MEN1KMT2AHSD17B10LMNACYP1A2 | |
| SCHEMBL23020769 | 0.67 | LMNA (0.41) | LMNAKDM4ENOS3NOS1NOS2 | |
| SCHEMBL22229900 | 0.67 | ALDH1A1 (0.51) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402781-B1 | 3-((HETERO-)ARYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |