Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566750 | 0.94 | KMT2A (0.58) | KMT2APARP10MAPTNPSR1ALDH1A1 | |
| SCHEMBL3102478 | 0.88 | ALDH1A1 (0.53) | KMT2APARP10CA1CA2MAPT | |
| SCHEMBL5527403 | 0.83 | KMT2A (0.46) | KMT2APARP10MAPTNPSR1ALDH1A1 | |
| SCHEMBL2936991 | 0.81 | CA12 (0.37) | KMT2APARP10CA12CA1CA2 | |
| SCHEMBL5747150 | 0.79 | KMT2A (0.63) | KMT2APARP10MAPTALDH1A1POLB | |
| SCHEMBL5943354 | 0.79 | KMT2A (0.63) | KMT2APARP10CA12CA1CA2 | |
| SCHEMBL3089210 | 0.77 | ALDH1A1 (0.62) | KMT2APARP10CA1CA2MAPT | |
| Hydroquinone SCHEMBL8984334 | 0.77 | KMT2A (0.85) | KMT2APARP10CA12CA1CA2 | |
| SCHEMBL7855318 | 0.77 | ALOX15 (0.48) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL28485 | 0.76 | KMT2A (0.56) | KMT2APARP10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-03-04 | — | — | EP | disclosed |