Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035502 | 0.79 | TUBB1 (0.72) | MAOBERN1TUBB1MAOANPC1 | |
| SCHEMBL2090976 | 0.76 | MAOB (0.62) | MAOBTOP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL18623122 | 0.76 | MAOB (0.62) | MAOBNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL435043 | 0.76 | ALDH1A1 (0.61) | MAOBERN1TUBB1MAOANPC1 | |
| SCHEMBL13802180 | 0.75 | MAOB (0.60) | MAOBTUBB1MAOANPC1RAB9A | |
| SCHEMBL8184228 | 0.75 | MAOB (0.60) | MAOBTUBB1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL30148511 | 0.75 | MAOB (0.60) | MAOBTUBB1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL3119532 | 0.74 | MAOB (0.55) | MAOBMAOARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL5728865 | 0.74 | MAOB (0.58) | MAOBTUBB1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL18044481 | 0.74 | MAOB (0.58) | MAOBL3MBTL1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-03-04 | — | — | EP | disclosed |