Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12577524 | 0.72 | RAB9A (0.57) | MAPTRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL16397928 | 0.72 | ALOX15 (0.45) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL16397926 | 0.72 | ALOX15 (0.45) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL8096846 | 0.71 | SLC6A4 (0.49) | MAPTHSD17B10POLBTSHR | |
| SCHEMBL7828978 | 0.71 | SLC6A4 (0.49) | MAPTHSD17B10POLBTSHR | |
| SCHEMBL28348174 | 0.71 | PDE4B (0.47) | RAB9AALDH1A1TP53GAASMN1; SMN2 | |
| SCHEMBL21768005 | 0.71 | PDE4B (0.47) | RAB9AALDH1A1TP53GAASMN1; SMN2 | |
| SCHEMBL21768003 | 0.71 | PDE4B (0.47) | RAB9AALDH1A1TP53GAASMN1; SMN2 | |
| SCHEMBL8096658 | 0.67 | AKR1C3 (0.44) | RAB9ANPC1ALDH1A1KMT2AGAA | |
| SCHEMBL7824679 | 0.67 | AKR1C3 (0.44) | RAB9ANPC1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616692-A1 | PHARMACEUTICAL COMPOSITION, CONTAINING NM23 ACTIVATOR, FOR INHIBITING CANCER METASTASIS | Ewha University-Industry Collaboration Foundation (KR) | 2020-03-04 | — | — | EP | disclosed |