Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CBX7 | O95931 | 1/20 | 0.31 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.31 |
| ▸ | CBX8 | Q9HC52 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781939 | 0.82 | AKT1 (0.37) | AKT1CYP3A4LCKITGB1ITGA5 | |
| SCHEMBL21782018 | 0.81 | AKT1 (0.37) | AKT1CYP3A4QRFPROPRM1OPRD1 | |
| SCHEMBL21782113 | 0.81 | AKT1 (0.41) | AKT1CYP3A4OPRM1OPRD1LCK | |
| SCHEMBL21781948 | 0.78 | AKT1 (0.41) | AKT1CYP3A4OPRM1OPRD1LCK | |
| SCHEMBL21782075 | 0.78 | AKT1 (0.40) | AKT1CYP3A4OPRM1OPRD1LCK | |
| SCHEMBL21781926 | 0.77 | AKT1 (0.42) | AKT1LCKITGB1ITGA5PSMB8 | |
| SCHEMBL22561364 | 0.77 | KDM1A (0.39) | AKT1LCKITGB1ITGA5 | |
| SCHEMBL21781883 | 0.76 | AKT1 (0.40) | AKT1CYP3A4OPRM1OPRD1LCK | |
| SCHEMBL21781778 | 0.76 | KLKB1 (0.40) | AKT1LCK | |
| SCHEMBL21781988 | 0.74 | KDM1A (0.41) | AKT1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |